Crohn's disease, relapsing polychondritis and epidermolysis bullosa acquisita: an immune-mediated inflammatory syndrome.

thickness skin graft to a large surgical wound in a patient with sclerodermatous skin. In this case history, the key point is a clinical one—that wound healing may be uncomplicated even if the graft is taken from affected sclerodermatous skin and transplanted to another affected area. There are reports in the literature of using artificial [8], split thickness [9] and autologous [10] skin grafts to promote ulcer healing in patients with SSc. In conclusion, in this case, primary closure of the wound was impossible, and there was a real concern that our patient might have required amputation. Grafted skin presented a natural barrier for preventing infection and allowed early wound healing. Our patient thus demonstrates how split thickness skin grafting even from sclerodermatous skin can be successfully used to cover large wounds with a good outcome in patients with SSc.